A Clinicopathological Study of Malignant Insulinoma in a Contemporary Series

  title={A Clinicopathological Study of Malignant Insulinoma in a Contemporary Series},
  author={R. Yu and N. Nissen and A. Hendifar and L. Tang and Yu-Li Song and Yuan-Jia Chen and X. Fan},
  • R. Yu, N. Nissen, +4 authors X. Fan
  • Published 2017
  • Medicine
  • Pancreas
  • Objective The aim of the study was to address the origin and natural history of malignant insulinoma. Methods Retrospective review of medical records of patients diagnosed with insulinoma at Cedars-Sinai Medical Center between 2000 and 2015 was conducted. Hormonal expression in tumor specimens was examined by immunostaining. Results All the 9 patients with malignant insulinoma (35% of 26 patients with insulinoma) already had liver metastasis at hypoglycemia presentation with bulky cumulative… CONTINUE READING
    7 Citations
    Insulinoma: A retrospective study analyzing the differences between benign and malignant tumors.
    • 7
    Distinct clinicopathological and prognostic features of insulinoma with synchronous distant metastasis.
    • H. Gao, W. Wang, +7 authors L. Liu
    • Medicine
    • Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
    • 2019
    • 3
    Surgical management, pre-operative tumor localization and histopathology of 80 patients operated for insulinoma.
    • 5
    Prognostic relevance of UCH-L1 and α-internexin in pancreatic neuroendocrine tumors
    • 9
    • PDF


    Malignant Metastatic Insulinoma—Postoperative Treatment and Follow-up
    • 53
    • PDF
    Metastatic nonfunctioning pancreatic neuroendocrine carcinoma to liver: surgical treatment and outcomes.
    • 55
    Chromosomal instability predicts metastatic disease in patients with insulinomas.
    • 69
    • PDF
    Efficacy of everolimus in patients with metastatic insulinoma and refractory hypoglycemia.
    • 70
    • PDF