A Clinically Useful Method for Detecting Gonadotropins in Children: Assessment of Luteinizing Hormone and Follicle-Stimulating Hormone from Urine as an Alternative to Serum by Ultrasensitive Time-Resolved Immunofluorometric Assays


ABSTRACT: To study the feasibility of noninvasive sampling in pediatric patients, we examined the concentrations of LH and FSH in paired serum and urine samples from 65 children (age 0–15 y) with highly sensitive time-resolved immunofluorometric assays. The detection limits of the assays were 0.015 lU/L for LH and 0.018 lU/L for FSH. These sensitivity… (More)
DOI: 10.1203/00006450-199408000-00014


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