A Clinical and Neurobehavioural Review of High-Functioning Autism and Asperger's Disorder

@article{Rinehart2002ACA,
  title={A Clinical and Neurobehavioural Review of High-Functioning Autism and Asperger's Disorder},
  author={Nicole J Rinehart and John L. Bradshaw and Avril Vaux Brereton and Bruce J. Tonge},
  journal={Australian and New Zealand Journal of Psychiatry},
  year={2002},
  volume={36},
  pages={762 - 770}
}
Objective: To compare, contrast and review clinical and neuropsychological studies of highfunctioning autism and Asperger's disorder. Method: This paper reviews past and contemporary conceptualizations of autism and Asperger's disorder, together with epidemiological information, genetic and neurobehavioural findings. This paper focuses on neurobehavioural studies, in particular, executive functioning, lateralization, visual-perceptual and motor processing, which have provided an important… 
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References

SHOWING 1-10 OF 97 REFERENCES
A neurobehavioral examination of individuals with high-functioning autism and Asperger's disorder using a fronto-striatal model of dysfunction.
TLDR
Whereas the Asperger's disorder group performed similarly to age- and IQ-matched control participants, even at the higher levels of cognitive complexity, the high-functioning autism group displayed inhibitory deficits specifically associated with increasing cognitive load.
Asperger's syndrome and autism: neurocognitive aspects.
TLDR
Whether children with Asperger's Syndrome have similar neurocognitive deficits compared to nonretarded, or high-functioning autistic children; and whether the essential cognitive deficit among these children is in language or abstract problem solving are examined.
ASPERGER'S SYNDROME AND AUTISM: COMPARISON OF EARLY HISTORY AND OUTCOME
TLDR
There were no substantive, qualitative differences between the AS and autistic groups, indicating that AS should be considered a mild form of high‐functioning autism, and the inclusion of AS among the autistic spectrum of disorders has implications for aetiological studies and for prevalence estimates of the pervasive developmental disorders.
Behavioural and Emotional Disturbance in High-Functioning Autism and Asperger Syndrome
TLDR
It was found that children and adolescents with Asperger's disorder presented with higher levels of psychopathology than those with high-functioning autism, were more disruptive, antisocial and anxious, and had more problems with social relationships.
Autism, affective and other psychiatric disorders: patterns of familial aggregation
TLDR
The results indicated that OCD, but not affective disorders, may index an underlying liability to autism, and that the increased risk of affective Disorders was not solely the consequence of the stress of raising a child with autism and that further research will be required to clarify the mechanisms involved.
Movement Preparation in High-Functioning Autism and Asperger Disorder: A Serial Choice Reaction Time Task Involving Motor Reprogramming
TLDR
The results indicated that individuals with autism and Asperger disorder have atypical movement preparation with an intact ability to execute movement.
Executive functions and developmental psychopathology.
TLDR
It is revealed that EF deficits are consistently found in both ADHD and autism but not in CD (without ADHD) or in TS, and both the severity and profile of EF deficits appears to differ across ADHD and Autism.
Atypical interference of local detail on global processing in high-functioning autism and Asperger's disorder.
TLDR
Global processing in children and adolescents with autism and Asperger's disorder was more vulnerable when the local stimuli were incongruent, and the neurobiological significance of these findings were discussed in the context of a fronto-striatal model of dysfunction.
Asperger's syndrome: evidence of an empirical distinction from high-functioning autism.
TLDR
This study compared the neuropsychological profiles of individuals with high-functioning autism (HFA) and Asperger's syndrome (AS) and suggests that HFA and AS are empirically distinguishable on measures independent of diagnostic criteria.
Brief report: A reappraisal of clumsiness as a diagnostic feature of Asperger syndrome
TLDR
It is generally accepted that the core features of the syndrome consist of social isolation, odd and pedantic speech, poor nonverbal communication, and preoccupation with certain idiosyncratic interests and clumsiness has been proposed as one of the diagnostic criteria.
...
...