A Clinical Perspective on Ethical Issues in Genetic Testing

  title={A Clinical Perspective on Ethical Issues in Genetic Testing},
  author={R. Sijmons and I. Van Langen and J. G. Sijmons},
  journal={Accountability in Research},
  pages={148 - 162}
Genetic testing is traditionally preceded by counselling to discuss its advantages and disadvantages with individuals so they can make informed decisions. The new technique of whole genome or exome sequencing, which is currently only used in research settings, can identify many gene mutations, including substantial numbers of mutations with unknown pathological effect; it may, therefore, threaten this balanced approach if it is used in a clinical setting. We discuss the ethical challenges of… Expand
20 Citations

Topics from this paper

“I want to know what's in Pandora's box”: Comparing stakeholder perspectives on incidental findings in clinical whole genomic sequencing
  • 136
  • Highly Influenced
Disclosing incidental findings in genetics contexts: a review of the empirical ethical research.
  • 31
  • PDF
My Identical Twin Sequenced our Genome
  • 2


Prenatal diagnosis and the trouble with eugenics.
  • L. Landeweerd
  • Medicine
  • Revista de derecho y genoma humano = Law and the human genome review
  • 2009
  • 2
Ethical implications of array comparative genomic hybridization in complex phenotypes: points to consider in research
  • 46
  • PDF
Ethical issues in new uses of preimplantation genetic diagnosis
  • 41
Clinical implementation of pharmacogenomics: overcoming genetic exceptionalism.
  • 88
Extending preimplantation genetic diagnosis: the ethical debate. Ethical issues in new uses of preimplantation genetic diagnosis.
  • 147
  • PDF
Confidentiality and sharing genetic information with relatives
  • 29
Preimplantation genetic diagnosis (PGD) in Europe: diversity of legislation a challenge to the community and its citizens.
  • S. Soini
  • Psychology, Medicine
  • Medicine and law
  • 2007
  • 24
Anticipating issues related to increasing preimplantation genetic diagnosis use: a research agenda.
  • 22
Genetic testing in primary care.
  • W. Burke
  • Medicine
  • Annual review of genomics and human genetics
  • 2004
  • 62
Ethical, legal, and practical concerns about recontacting patients to inform them of new information: the case in medical genetics.
  • 56