A Chlamydomonas reinhardtii UV-sensitive mutant uvs15 is impaired in a gene involved in several repair pathways.

@article{Vlek1997ACR,
  title={A Chlamydomonas reinhardtii UV-sensitive mutant uvs15 is impaired in a gene involved in several repair pathways.},
  author={Daniel Vl{\vc}ek and A Slivkov{\'a} and Svetlana Podstavkov{\'a} and Eva Miadokov{\'a}},
  journal={Mutation research},
  year={1997},
  volume={385 3},
  pages={243-9}
}
In this report, three DNA repair-deficient mutants of Chlamydomonas reinhardtii (uvs13, uvs14, uvs15) were characterized by using genetic, mutational and biochemical analyses. The mutant strain uvs15 belongs to the most sensitive repair-deficient mutants following exposure to all agents used. It is deficient in the nuclear excision-repair pathway, whereas uvs13 and uvs14 are not blocked in removal of pyrimidine dimers. Mutation study also revealed differences among strains. The mutant uvs15… CONTINUE READING