A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects.

Abstract

Mouse models provide important resources for many areas of vision research, pertaining to retinal development, retinal function and retinal disease. The Translational Vision Research Models (TVRM) program uses chemical mutagenesis to generate new mouse models for vision research. In this chapter, we report the identification of mouse models for Grm1, Grk1 and Lrit3. Each of these is characterized by a primary defect in the electroretinogram. All are available without restriction to the research community.

DOI: 10.1007/978-3-319-17121-0_24

Cite this paper

@article{Charette2016ACM, title={A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects.}, author={Jeremy R. Charette and Ivy S. Samuels and Minzhong Yu and Lisa Stone and Wanda L. Hicks and Lan Ying Shi and Mark P Krebs and J{\"{u}rgen K Naggert and Patsy M. Nishina and Neal S. Peachey}, journal={Advances in experimental medicine and biology}, year={2016}, volume={854}, pages={177-83} }