A Central Role of Salicylic Acid in Plant Disease Resistance

@article{Delaney1994ACR,
  title={A Central Role of Salicylic Acid in Plant Disease Resistance},
  author={Terrence P. Delaney and Scott Uknes and Bernard Vernooij and Leslie Friedrich and Kris Weymann and David Vincent Negrotto and Tom Gaffney and Manuela Gut-Rella and Helmut Kessmann and Eric R Ward and John A. Ryals},
  journal={Science},
  year={1994},
  volume={266},
  pages={1247 - 1250}
}
Transgenic tobacco and Arabidopsis thaliana expressing the bacterial enzyme salicylate hydroxylase cannot accumulate salicylic acid (SA). This defect not only makes the plants unable to induce systemic acquired resistance, but also leads to increased susceptibility to viral, fungal, and bacterial pathogens. The enhanced susceptibility extends even to host-pathogen combinations that would normally result in genetic resistance. Therefore, SA accumulation is essential for expression of multiple… 
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Induced plant resistance and salicylic acid: A review
TLDR
The mechanism whereby SA induces plant resistance depends on the ability of this compound to inhibit the enzymes of the antioxidant system of plants, which results in the accumulation of active oxygen species and the expression of defense genes.
An update on salicylic acid biosynthesis, its induction and potential exploitation by plant viruses.
Overproduction of salicylic acid in plants by bacterial transgenes enhances pathogen resistance
TLDR
Tobacco is transformed with two bacterial genes coding for enzymes that convert chorismate into SA by a two-step process and the CSA plants showed a resistance to viral and fungal infection resembling SAR in nontransgenic plants.
The Role of Salicylic Acid in Systemic Resistance of Tomato to Nematodes
TLDR
The development of resistance in tissues of vegetating plants after presowing treatment of the plant seeds with elicitors is a manifestation of SIR.
Ethylene-dependent salicylic acid regulates an expanded cell death response to a plant pathogen.
TLDR
A mechanism for co-ordination of phytohormone signals that together constitute a susceptible response to pathogens are indicated.
The role of salicylic acid and jasmonic acid in pathogen defence.
TLDR
The role of salicylic acid and jasmonic acid in pathogen defence responses with special emphasis on their function in the solanaceous plant potato is reviewed.
Signaling of systemic acquired resistance in tobacco depends on ethylene perception.
TLDR
It is concluded that ethylene perception is required to generate the systemic signal molecules in TMV-infected leaves that trigger SA accumulation, defense gene expression, and SAR development in uninfected leaves.
The Molecular Biology of Systemic Acquired Resistance
Depletion of in planta salicylic acid in transgenic salicylate hydroxylase (NahG)­containing plants, has shown that this phenolic compound is essential for expression of several modes of plant…
Abscisic acid activates pathogenesis-related defence gene signalling in Lentil
TLDR
Plants exhibit complex defense responses against pathogens to either prevent them from entering the plant or obtaining nutrients for growth and reproduction, which may be pre-formed and/or induced.
Salicylate-independent lesion formation in Arabidopsis lsd mutants.
TLDR
The loss of SAR gene expression and disease resistance in nahG-expressing lsd mutants indicates that these traits are dependent upon SA accumulation in the SAR signal transduction pathway.
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References

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Salicylic acid is essential for the development of systemic acquired resistance in tobacco and was investigated in transgenic tobacco plants harboring a bacterial gene encoding salicylate hydroxylase.
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TLDR
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