A Central Action of Hemicholinium

@article{Quastel1965ACA,
  title={A Central Action of Hemicholinium},
  author={David M. J. Quastel and David R. Curtis},
  journal={Nature},
  year={1965},
  volume={208},
  pages={192-194}
}
THE action of hemicholinium No. 3 (α-α-dimethylethanolamine 4,4′-bisacetophenone, HC 3) on the synaptic release of acetylcholine at the neuromuscular junction and within autonomic ganglia is well established1. However, apart from the finding that intravenously administered HC 3 reduces the acetylcholine content of the pons and medulla of dogs2, and the report that locally administered HC 3 reduces the content and synthesis of acetylcholine within the caudate nucleus of rats3, there is yet no… CONTINUE READING

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