A Causal Role for Bdnf in the Homeostatic Regulation of Sleep

Abstract

Slow wave activity (SWA), the EEG power between 0.5 4 Hz during NREM sleep, is one of the best characterized markers of sleep need, as it increases as a function of preceding waking duration and decreases during sleep, but the underlying mechanisms remain unknown. We hypothesized that SWA is high at sleep onset because it reflects the occurrence, during the… (More)

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