A Case Report of Propofol Dependence in a Physician

@article{Bonnet2008ACR,
  title={A Case Report of Propofol Dependence in a Physician},
  author={Udo Bonnet and J{\"o}rg Harkener and Norbert Scherbaum},
  journal={Journal of Psychoactive Drugs},
  year={2008},
  volume={40},
  pages={215 - 217}
}
Abstract Propofol is a widely used general anaesthetic with multisite mechanisms and especially ultrashort activation of certain central GABA-A receptors. Since its introduction into the market in the mid 1980s this is the seventh report on propofol dependence in the literature. The present case shows for the first time that craving for propofol can be quite intense and able to induce addictive behaviour. 
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The agents used to induce or maintain general anesthesia have been shown time and time again, in multiple studies involving both humans and animals, to carry considerable abuse liability. These drugs
Abuse of Propofol by Anesthesia Providers: The Case for Re‐Classification as a Controlled Substance
TLDR
Control of propofol will not decrease the overall incidence of substance abuse among health professionals, but it will prevent many accidental deaths.
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TLDR
An exploration of reported objective and subjective patterns in propofol abuse case reports was conducted using a modified process of thematic (pattern) analysis, finding patterns including: healthcare providers are the most frequent prop ofol abusers.
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TLDR
Propofol is a safe anesthetic agent, but propofol infusion syndrome is a rare lethal complication that offers advantages over traditional anesthetics in clinical situations in which rapid recovery is important.
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TLDR
The pharmacology and misuse/abuse potential of propofol and the influence of the 12-step recovery paradigm in the re-entry literature are reviewed and existing research and policy are drawn upon to suggest employment re- entry guidelines for healthcare workers.
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