A Carbohydrate-Derived Splice Modulator.

@article{Dhar2016ACS,
  title={A Carbohydrate-Derived Splice Modulator.},
  author={Sachin Dhar and James J La Clair and Brian Le{\'o}n and Justin C Hammons and Zhe Yu and Manoj Kumar Kashyap and Januario E. Castro and Michael D. Burkart},
  journal={Journal of the American Chemical Society},
  year={2016},
  volume={138 15},
  pages={5063-8}
}
Small-molecule splice modulators have recently been recognized for their clinical potential for diverse cancers. This, combined with their use as tools to study the importance of splice-regulated events and their association with disease, continues to fuel the discovery of new splice modulators. One of the key challenges found in the current class of… CONTINUE READING