A COMPREHENSION INTO TARGET BINDING AND SPATIAL FINGERPRINTS OF NOSCAPINOID ANALOGUES AS INHIBITORS OF TUBULIN.

@article{Mandavi2020ACI,
  title={A COMPREHENSION INTO TARGET BINDING AND SPATIAL FINGERPRINTS OF NOSCAPINOID ANALOGUES AS INHIBITORS OF TUBULIN.},
  author={Seema Mandavi and Renu Bhatt and Santosh Kumar Verma and Laxmi Banjare and Amit Dubey and Suresh Thareja and Akhlesh Kumar Jain},
  journal={Medicinal chemistry (Shariqah (United Arab Emirates))},
  year={2020}
}
AIM The present research aims to insight into target binding and mapping of spatial fingerprints of noscapinoids as inhibitors of tubulin. BACKGROUND Owing to its potential to interfere in microtubule dynamics in mitotic phase of cell cycle and selectively inducing apoptosis in cancer cells without affecting normal cells, noscapine and its synthetic analogues have been investigated by other research groups in different cell lines for their capability to use as anti-cancer agents. OBJECTIVE…