A CMOS capacitance sensor that monitors cell viability

@article{Prakash2005ACC,
  title={A CMOS capacitance sensor that monitors cell viability},
  author={S. Prakash and P. A. Abshire},
  journal={IEEE Sensors, 2005.},
  year={2005},
  pages={4 pp.-}
}
We describe a CMOS capacitance sensor for measuring the capacitive behavior of living cells in a culture environment, in the presence of weak electric fields. The underlying physical phenomenon results primarily from polarization of the ionic cloud surrounding the cell in aqueous medium. The measured capacitance depends on a variety of factors including cell morphology, membrane integrity, medium pH and extra cellular ionic concentration and serves as an indicator of cell health. The… CONTINUE READING
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