A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance.

@article{AgetaIshihara2015ACP,
  title={A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance.},
  author={Natsumi Ageta-Ishihara and Maya Yamazaki and Kohtarou Konno and Hisako Nakayama and Manabu Abe and Kenji Hashimoto and Tomoki Nishioka and Kozo Kaibuchi and Satoko Hattori and Tsuyoshi Miyakawa and Kohichi Tanaka and Fathul Huda and Hirokazu Hirai and Kouichi Hashimoto and Masahiko Watanabe and Kenji Sakimura and Makoto Kinoshita},
  journal={Nature communications},
  year={2015},
  volume={6},
  pages={10090}
}
The small GTPase-effector proteins CDC42EP1-5/BORG1-5 interact reciprocally with CDC42 or the septin cytoskeleton. Here we show that, in the cerebellum, CDC42EP4 is exclusively expressed in Bergmann glia and localizes beneath specific membrane domains enwrapping dendritic spines of Purkinje cells. CDC42EP4 forms complexes with septin hetero-oligomers, which… CONTINUE READING