A CD99-related antigen on endothelial cells mediates neutrophil but not lymphocyte extravasation in vivo.

@article{Bixel2007ACA,
  title={A CD99-related antigen on endothelial cells mediates neutrophil but not lymphocyte extravasation in vivo.},
  author={Maria Gabriele Bixel and Bj{\"o}rn Petri and Alexander Georg Khandoga and Andrej Khandoga and Karen Wolburg-Buchholz and Hartwig Wolburg and Sigrid Maerz and Fritz Krombach and Dietmar Vestweber},
  journal={Blood},
  year={2007},
  volume={109 12},
  pages={5327-36}
}
CD99 is a long-known leukocyte antigen that does not belong to any of the known protein families. It was recently found on endothelial cells, where it mediates transendothelial migration of human monocytes and lymphocyte recruitment into inflamed skin in the mouse. Here, we show that CD99L2, a recently cloned, widely expressed antigen of unknown function with moderate sequence homology to CD99, is expressed on mouse leukocytes and endothelial cells. Using antibodies, we found that CD99L2 and… CONTINUE READING

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