A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity.

Abstract

MicroRNAs (miRNAs) and transcription factors (TFs) are primary metazoan gene regulators. Whereas much attention has focused on finding the targets of both miRNAs and TFs, the transcriptional networks that regulate miRNA expression remain largely unexplored. Here, we present the first genome-scale Caenorhabditis elegans miRNA regulatory network that contains… (More)
DOI: 10.1101/gad.1678608

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