A C-terminal, cysteine-rich site in poliovirus 2C(ATPase) is required for morphogenesis.

Abstract

The morphogenesis of viruses belonging to the genus Enterovirus in the family Picornaviridae is still poorly understood despite decades-long investigations. However, we recently provided evidence that 2C(ATPase) gives specificity to poliovirus encapsidation through an interaction with capsid protein VP3. The polypeptide 2C(ATPase) is a highly conserved non… (More)
DOI: 10.1099/vir.0.062497-0

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