A Brief History of Carbon Monoxide and Its Therapeutic Origins.

@article{Hopper2021ABH,
  title={A Brief History of Carbon Monoxide and Its Therapeutic Origins.},
  author={Christopher P. Hopper and Paige N Zambrana and Ulrich Goebel and Jakob Wollborn},
  journal={Nitric oxide : biology and chemistry},
  year={2021}
}
It is estimated that 10% of carbon throughout the cosmos is in the form of carbon monoxide (CO) [1]. Earth's earliest prebiotic atmosphere included the trinity of gasotransmitters CO, nitric oxide (NO), and hydrogen sulfide (H2S), for which all of life has co-evolved with [2]. Speculation for extraterrestrial life in harsh environments is similarly based on harnessing atmospheric CO as a primary energy source [3]. The history of CO can be loosely traced to mythological and prehistoric origins… 
1 Citations
Gasotransmitters for the Therapeutic Prevention of Hypertension and Kidney Disease
TLDR
The current knowledge of NO, CO, and H2S implicated in pregnancy, including in physiological and pathophysiological processes, is described, highlighting their key roles in hypertension and kidney disease.

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