A Borrelia-specific monoclonal antibody binds to a flagellar epitope.

  title={A Borrelia-specific monoclonal antibody binds to a flagellar epitope.},
  author={Alan G Barbour and Stanley F. Hayes and Ramona A. Heiland and Merry E. Schrumpf and S L Tessier},
  journal={Infection and immunity},
  volume={52 2},
In immunofluorescence assays monoclonal antibody H9724 recognized eight species of the spirochetal genus Borrelia but not representatives of the genera Treponema, Leptospira, and Spirochaeta. We examined the reactivity of H9724 against subcellular components of Borrelia hermsii, an agent of relapsing fever, and B. burgdorferi, the cause of Lyme disease. H9724 bound to isolated periplasmic flagella of the two borreliae. In Western blots the antibody reacted with the predominant protein in… CONTINUE READING
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