A Boost for HIV Vaccine Design

@article{Burton2010ABF,
  title={A Boost for HIV Vaccine Design},
  author={Dennis R. Burton and Robin A. Weiss},
  journal={Science},
  year={2010},
  volume={329},
  pages={770 - 773}
}
Antibodies that potently neutralize almost all HIV isolates could aid the rational design of a vaccine. A major roadblock to the development of an effective vaccine against the human immunodeficiency virus (HIV-1) is the lack of an immunogen that elicits broadly protective antibodies (1). Passive transfer studies in animal models have associated protection with neutralizing antibodies and, encouragingly, serum studies show that a subset of HIV-infected individuals produces potent broadly… 
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