A Blood RNA Signature Detecting Severe Disease in Young Dengue Patients at Hospital Arrival

@inproceedings{Nikolayeva2018ABR,
  title={A Blood RNA Signature Detecting Severe Disease in Young Dengue Patients at Hospital Arrival},
  author={Iryna Nikolayeva and Pierre Bost and Isabelle Casad{\'e}mont and Veasna Duong and Fanny Koeth and Matthieu Prot and Urszula Czerwinska and Sowath Ly and Kevin Bleakley and Tineke Cantaert and Philippe Dussart and Philippe Buchy and Etienne Simon-Lori{\`e}re and Anavaj Sakuntabhai and Benno Schwikowski},
  booktitle={The Journal of infectious diseases},
  year={2018}
}
Background Early detection of severe dengue can improve patient care and survival. To date, no reliable single-gene biomarker exists. We hypothesized that robust multigene signatures exist. Methods We performed a prospective study on Cambodian dengue patients aged 4 to 22 years. Peripheral blood mononuclear cells (PBMCs) were obtained at hospital… CONTINUE READING