A Bir1p Sli15p kinetochore passenger complex regulates septin organization during anaphase.

@article{Thomas2007ABS,
  title={A Bir1p Sli15p kinetochore passenger complex regulates septin organization during anaphase.},
  author={Scott Thomas and Kenneth B. Kaplan},
  journal={Molecular biology of the cell},
  year={2007},
  volume={18 10},
  pages={
          3820-34
        }
}
Kinetochore-passenger complexes in metazoans have been proposed to coordinate the segregation of chromosomes in anaphase with the induction of cytokinesis. Passenger protein homologues in the budding yeast Saccharomyces cerevisiae play a critical role early in mitosis, ensuring proper biorientation of kinetochore-microtubule attachments. Our recent work has implicated the passenger protein Bir1p (Survivin) and the inner kinetochore complex centromere binding factor 3 (CBF3) in the regulation of… CONTINUE READING

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