A Biotin Phosphoramidite Reagent for the Automated Synthesis of 5′-Biotinylated Oligonucleotides

@inproceedings{Zhao1999ABP,
  title={A Biotin Phosphoramidite Reagent for the Automated Synthesis of 5′-Biotinylated Oligonucleotides},
  author={Zhengyun Zhao and J. F. Ackroyd},
  year={1999}
}
Abstract A bis(DMTr)biotin phosphoramidite containing serine and 6-aminohexanol moieties was prepared by a multiple-step reaction, and used successfully in the solid phase synthesis of 5′-biotinylated oligonucleotides.