A Bioguided Approach for the Screening of Antibacterial Compounds Isolated From the Hydroalcoholic Extract of the Native Brazilian Bee’s Propolis Using Mollicutes as a Model

  title={A Bioguided Approach for the Screening of Antibacterial Compounds Isolated From the Hydroalcoholic Extract of the Native Brazilian Bee’s Propolis Using Mollicutes as a Model},
  author={Sabrina Hochheim and Pamela Pacassa Borges and Ariela Ma{\'i}na Boeder and D. R. Scharf and E. Simionatto and C. N. Yamanaka and M. D. Alberton and A. Guedes and C. M. D. de Cordova},
  journal={Frontiers in Microbiology},
Nature is a vast source of medicinal substances, including propolis, which has been extensively investigated. Propolis is a resinous substance produced by bees from the exudates of plants that they collect and modify in their jaws; it is a rich and complex matrix with secondary metabolites of diverse botanical origins. The objective of this study was to apply an in vitro bioguided approach using as a model system the mollicutes with a sample of propolis from the Brazilian native bee Melipona… Expand
3 Citations
Mollicute Anti‐Adhesive and Growth Inhibition Properties of the Methanolic Extract of Propolis from the Brazilian Native Bee Melipona quadrifasciata
A synergistic effect of the nonpolar compounds in M. quadrifasciata propolis may be responsible for its antibacterial activity, but several purified components can improve its anti‐adhesive properties. Expand
Antimicrobial activity of flavonoids glycosides and pyrrolizidine alkaloids from propolis of Scaptotrigona aff. postica
Fractions 40 AEP and 40 MEP showed antimicrobial activity against Gram negative bacteria, including Escherichia coli D31-streptomycin resistant and cell viability was expressed in terms of the relative absorbance of treated and untreated cells (control). Expand
Apitherapy for Age-Related Skeletal Muscle Dysfunction (Sarcopenia): A Review on the Effects of Royal Jelly, Propolis, and Bee Pollen
This review examines the literature for possible effects of royal jelly, bee pollen, and propolis on skeletal muscle in aged experimental models, muscle cell cultures, and humans and offers suggestions for other mechanisms to be explored and provides guidance for future trials investigating the effects of bee products among people with sarcopenia. Expand


Determination of phenolic profile by HPLC–ESI-MS/MS, antioxidant activity, in vitro cytotoxicity and anti-herpetic activity of propolis from the Brazilian native bee Melipona quadrifasciata
Abstract Propolis is a rich source of bioactive molecules made by bees by collecting an infinite variety of secondary metabolites from plants. This study determined the chromatographic and massExpand
Chemical Composition and Biological Activity of Propolis from Brazilian Meliponinae
The results confirm that neither the bee species nor the geographical location determine the chemical composition of Meliponinae propolis and the choice of its plant source, respectively. Expand
Antibacterial mono- and sesquiterpene esters of benzoic acids from Iranian propolis
The results of the present study are consistent with the idea that propolis from unexplored regions is a promising source of biologically active compounds. Expand
RP-HPLC analysis of manool-rich Salvia officinalis extract and its antimicrobial activity against bacteria associated with dental caries
The results evidenced that the manool-rich S. officinalis extract can be considered an analytically validated alternative to develop novel and effective antimicrobial agents against the main bacteria responsible for dental caries. Expand
Recent Progress of Propolis for Its Biological and Chemical Compositions and Its Botanical Origin
This paper presents a review on the publications on propolis and patents of applications and biological constituents of propolis. Expand
The specific chemical profile of Mediterranean propolis from Malta
It is confirmed that Mediterranean propolis is a valuable natural product with potential to improve human health and its origin is suggested to be Ferula communis, as they are taxonomic markers for this species. Expand
Czech ethanol-free propolis extract displays inhibitory activity against a broad spectrum of bacterial and fungal pathogens.
Evaluation of DMSO propolis extracts in experimental treatment of human and veterinary infections, preferably in multitherapy with antibiotics is suggested. Expand
Moroccan Propolis: A Natural Antioxidant, Antibacterial, and Antibiofilm against Staphylococcus aureus with No Induction of Resistance after Continuous Exposure
Propolis extract at the MIC value significantly reduced the virulence potential of S. aureus ATCC 6538 and the MRSA strains without leading to the development of resistance in the sequence of continuous exposure. Expand
Origin and Chemical Variation of Brazilian Propolis
Propolis research has uncovered potentialities of substances previously isolated from plants and has detected constituents of plant origin that would hardly be known otherwise. Expand
Propolis volatile compounds: chemical diversity and biological activity: a review
The role of propolis volatiles in identification of its plant origin is discussed, and the available data about chemical composition of propoli volatile from different geographic regions are reviewed, demonstrating significant chemical variability. Expand