A Bayesian measure of the probability of false discovery in genetic epidemiology studies.

@article{Wakefield2007ABM,
  title={A Bayesian measure of the probability of false discovery in genetic epidemiology studies.},
  author={Jonathan Wakefield},
  journal={American journal of human genetics},
  year={2007},
  volume={81 2},
  pages={208-27}
}
In light of the vast amounts of genomic data that are now being generated, we propose a new measure, the Bayesian false-discovery probability (BFDP), for assessing the noteworthiness of an observed association. BFDP shares the ease of calculation of the recently proposed false-positive report probability (FPRP) but uses more information, has a noteworthy threshold defined naturally in terms of the costs of false discovery and nondiscovery, and has a sound methodological foundation. In addition… CONTINUE READING
Highly Influential
This paper has highly influenced 19 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 142 extracted citations

Similar Papers

Loading similar papers…