• Chemistry
  • Published 2008

A Bayesian approach to tracking in single molecule fluorescence microscopy

@inproceedings{Yoon2008ABA,
  title={A Bayesian approach to tracking in single molecule fluorescence microscopy},
  author={Ji Won Yoon and Sumeetpal Singh},
  year={2008}
}
Using fluorescence microscopy with single molecule sensitivity it is now possible to follow the movement of individual fluorophore tagged molecules such as proteins and lipids in the cell membrane with nanometer precision. These experiments are important as they allow many key biological processes on the cell membrane and in the cell, such as transcription, translation and DNA replication, to be studied at new levels of detail. Computerized microscopes generate sequences of images (in the order… CONTINUE READING