A BRCA1 mutation in Native North American families.

  title={A BRCA1 mutation in Native North American families.},
  author={Alexander Liede and Elaine Jack and Robert A Hegele and Steven A Narod},
  journal={Human mutation},
  volume={19 4},
Germline mutations in the BRCA1 (MIM 113705) and BRCA2 (MIM 600185) genes have been identified for breast and ovarian cancer families of diverse ethnic backgrounds. To date, there have been no reports of Native North American families with mutations in BRCA1 or BRCA2. Here we report two families of aboriginal descent both with the same BRCA1 alterations… CONTINUE READING