A BAC-bacterial recombination method to generate physically linked multiple gene reporter DNA constructs

@article{Maye2009ABR,
  title={A BAC-bacterial recombination method to generate physically linked multiple gene reporter DNA constructs},
  author={Peter V. Maye and Mary Louise Stover and Ya-Ling Liu and David W. Rowe and Shiaoching Gong and Alexander C. Lichtler},
  journal={BMC Biotechnology},
  year={2009},
  volume={9},
  pages={20 - 20}
}
BACKGROUND Reporter gene mice are valuable animal models for biological research providing a gene expression readout that can contribute to cellular characterization within the context of a developmental process. With the advancement of bacterial recombination techniques to engineer reporter gene constructs from BAC genomic clones and the generation of optically distinguishable fluorescent protein reporter genes, there is an unprecedented capability to engineer more informative transgenic… CONTINUE READING

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