A 93-kDa glycoprotein expressed on human cultured monocytes and dendritic reticulum cells defined by an anti-K562 monoclonal antibody.

@article{Farace1986A9G,
  title={A 93-kDa glycoprotein expressed on human cultured monocytes and dendritic reticulum cells defined by an anti-K562 monoclonal antibody.},
  author={Françoise Farace and Nelly Kieffer and Bernard Caillou and William Vainchenker and Thomas Tursz and Marie Christine Dokhelar},
  journal={European journal of immunology},
  year={1986},
  volume={16 12},
  pages={1521-6}
}
An IgG2a monoclonal antibody, referred to as 12B1 and raised against the K562 cell line, reacted with adherent monocytes maintained in culture for several days but not with bone marrow or peripheral blood cells including freshly isolated monocytes. Among human leukemic cell lines, 12B1 reacted essentially with the promyelocytic HL60 cell line. 12-O-Tetradecanoylphorbol 13-acetate treatment, but no other differentiation inducer, strongly enhanced its reactivity on K562, HL60 and the histiocytic… CONTINUE READING