A 90-degree rotation of the mitotic spindle changes the orientation of mitoses of zebrafish neuroepithelial cells.

@article{GeldmacherVoss2003A9R,
  title={A 90-degree rotation of the mitotic spindle changes the orientation of mitoses of zebrafish neuroepithelial cells.},
  author={Benedikt Geldmacher-Voss and Alexander M. Reugels and Stefan Pauls and Jos{\'e} A. Campos-Ortega},
  journal={Development},
  year={2003},
  volume={130 16},
  pages={3767-80}
}
In the neural plate and neural tube in the trunk region of the zebrafish embryo, dividing cells are oriented parallel to the plane of the neuroepithelium, while in neural keel/rod, cells divide perpendicular to it. This change in the orientation of mitosis is brought about by a 90 degrees rotation of the mitotic spindle. As the two halves of the neural primordium in keel/rod stage are in apposition, the perpendicular orientation of mitoses in this stage determines that daughter cells become… CONTINUE READING

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