A 7-base-pair sequence protects DNA from exonucleolytic degradation in Lactococcus lactis.

@article{Biswas1995A7S,
  title={A 7-base-pair sequence protects DNA from exonucleolytic degradation in Lactococcus lactis.},
  author={Indranil Biswas and Emmanuelle Maguin and Stanislas Dusko Ehrlich and Alexandra Gruss},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1995},
  volume={92 6},
  pages={2244-8}
}
Linear DNA molecules are subject to degradation by various exonucleases in vivo unless their ends are protected. It has been demonstrated that a specific 8-bp sequence, 5'-GCTGGTGG-3', named Chi, can protect linear double-stranded DNA from the major Escherichia coli exonuclease RecBCD. Chi protects linear replication products of rolling-circle plasmids from… CONTINUE READING