A 60-kilodalton immunodominant glycoprotein is essential for cell wall integrity and the maintenance of cell shape in Streptococcus mutans.

@article{Chia2001A6I,
  title={A 60-kilodalton immunodominant glycoprotein is essential for cell wall integrity and the maintenance of cell shape in Streptococcus mutans.},
  author={J S Chia and Luan Yin Chang and C. T. Shun and Y. Y. Chang and Y G Tsay and Jin Yun Helen Chen},
  journal={Infection and immunity},
  year={2001},
  volume={69 11},
  pages={6987-98}
}
We have demonstrated previously by Western blotting that in naturally sensitized humans, the serum or salivary antibody response to Streptococcus mutans was directed predominantly to a protein antigen with a size of approximately 60-kDa. To identify this immunodominant antigen, specific serum antibodies were eluted from immunoblots and five positive clones with inserts ranging in length from 3 to 8 kb from identical chromosomal loci were obtained by screening a genomic expression library of… CONTINUE READING
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