A 6-month, open-label, extension study of the tolerability and effectiveness of the methylphenidate transdermal system in adolescents diagnosed with attention-deficit/hyperactivity disorder.

@article{Findling2010A6O,
  title={A 6-month, open-label, extension study of the tolerability and effectiveness of the methylphenidate transdermal system in adolescents diagnosed with attention-deficit/hyperactivity disorder.},
  author={Robert L. Findling and Alain Katic and Richard Rubin and Eliot Moon and Richard Civil and Yunfeng Li},
  journal={Journal of child and adolescent psychopharmacology},
  year={2010},
  volume={20 5},
  pages={365-75}
}
OBJECTIVE The aim of this study was to evaluate the tolerability and effectiveness of the methylphenidate transdermal system (MTS) over 6 months in adolescents with attention-deficit/hyperactivity disorder (ADHD). METHODS This was an industry-sponsored, 30-center, open-label study of subjects aged 13-17 years with ADHD. Subjects were dose-optimized with MTS (10-30 mg/9 hours) over 5 weeks and then dose-maintained for up to 5 months. Tolerability evaluations included treatment-emergent adverse… CONTINUE READING