A 55-kDa protein (p55) of the goat uterus mediates nuclear transport of the estrogen receptor. II. Details of the transport mechanism.

A 55-kDa protein (p55) that mediates the transport of the estrogen receptor (ER) from the cytoplasm to the nucleus has been purified to homogeneity from goat uterine cytosol. Using this pure protein, some of the aspects of the mechanisms associated with the transport of the ER to the nucleus have been elucidated. The mechanism of ER transport into the… CONTINUE READING