A 55,000 Mr surface antigen on activated human T lymphocytes defined by a monoclonal antibody.

@article{Hemler1983A5M,
  title={A 55,000 Mr surface antigen on activated human T lymphocytes defined by a monoclonal antibody.},
  author={Martin E Hemler and Bernard Malissen and Najet Rebai and Andr{\'e} Liabeuf and Claude E. Mawas and François M. Kourilsky and Jack Leonard Strominger},
  journal={Human immunology},
  year={1983},
  volume={8 2},
  pages={
          153-65
        }
}
A T cell growth factor-dependent alloreactive human T cell line has been used to generate a monoclonal antibody B1.49.9 that reacts with an antigen present on most if not all mitogen or alloantigen activated T cells but not on resting T cells. The T lymphoblastoid cell line HUT-102 is also strongly reactive with B1.49.9 but all other T and non-T leukemia-lymphoma cell lines tested were negative. The B1.49.9 antigen is a glycoprotein of 55,000 Mr on mitogen or alloantigen activated T cells and… CONTINUE READING

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