A 46-year-old Chinese woman presenting with retroperitoneal follicular dendritic cell sarcoma: a case report

Abstract

INTRODUCTION Follicular dendritic cells are non-phagocytic, non-lymphoid cells of the immune system that are necessary for antigen presentation and the regulation of reactions in the germinal centers of the lymph nodes. Follicular dendritic cell sarcoma is an unusual cancer, particularly in the intra-abdominal region. In the present report we describe an unusual case of retroperitoneal follicular dendritic cell sarcoma that emphasizes the difficulty of diagnosing and treating this tumor. Retroperitoneal follicular dendritic cell sarcoma has only been rarely reported in the literature to date. CASE PRESENTATION A 46-year-old Chinese woman of Han ethnicity presented with chronic right lower quadrant abdominal pain over the preceding 4 weeks. The tumor was resected and submitted to histopathological examination. The case was verified as retroperitoneal follicular dendritic cell sarcoma by microscopic examination and immunohistochemical analysis. After diagnosis, she received postoperative radiotherapy and chemotherapy. She has survived 3 years postoperatively, although she has a pulmonary metastasis. CONCLUSIONS Retroperitoneal follicular dendritic cell sarcoma may demonstrate aggressive potential. This study indicated that postoperative adjuvant radiotherapy and chemotherapy could extend the survival of a patient with retroperitoneal follicular dendritic cell sarcoma.

DOI: 10.1186/1752-1947-8-113

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@inproceedings{Yuan2014A4C, title={A 46-year-old Chinese woman presenting with retroperitoneal follicular dendritic cell sarcoma: a case report}, author={Taize Yuan and Qiuxiang Yang and Huanhuan Zhang and Jian Li and Xiuping Zhang}, booktitle={Journal of medical case reports}, year={2014} }