A 40-bp VNTR polymorphism in the 3′-untranslated region of DAT1/SLC6A3 is associated with ADHD but not with alcoholism

@inproceedings{er2015A4V,
  title={A 40-bp VNTR polymorphism in the 3′-untranslated region of DAT1/SLC6A3 is associated with ADHD but not with alcoholism},
  author={Omar {\vS}er{\'y} and Ivo Paclt and Ivana Drt{\'i}lkov{\'a} and Pavel Theiner and Marta Kope{\vc}kov{\'a} and Petr Zvolsk{\'y} and Vladimir Josef Balcar},
  booktitle={Behavioral and Brain Functions},
  year={2015}
}
ADHD and alcoholism are psychiatric diseases with pathophysiology related to dopamine system. DAT1 belongs to the SLC6 family of transporters and is involved in the regulation of extracellular dopamine levels. A 40 bp variable number tandem repeat (VNTR) polymorphism in the 3′-untranslated region of DAT1/SLC6A3 gene was previously reported to be associated with various phenotypes involving disturbed regulation of dopaminergic neurotransmission. A total of 1312 subjects were included and… CONTINUE READING
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  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND
HIGHLY INFLUENCED

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  • Neuroscience Bulletin
  • 2016
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 63 REFERENCES

Perspectives in genetic prediction of Alzheimer's disease.

  • Neuro endocrinology letters
  • 2014
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Polymorphisms in the dopamine transporter gene (SLC6A3/DAT1) and alcohol dependence in humans: a systematic review

CS van der Zwaluw, RC Engels, +3 authors RH. Scholte
  • Pharmacogenomics
  • 2009
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

NES2 User’s manual (version 4.7)

R. Letz
  • Atlanta: Neurobehavioral Systems,
  • 1998
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

A language and environment for statistical computing

R R Core Team
  • Vienna: R Foundation for Statistical Computing;
  • 2015
VIEW 1 EXCERPT

how applicable are public SNP databases to a typical European population? Eur J Hum Genet

B Jánošíková, P Zavadáková, metabolism Kožich V. Single-nucleotide polymorphisms in genes homocysteine
  • 2005;13:86–95. Šerý et al. Behavioral and Brain Functions
  • 2015
VIEW 1 EXCERPT

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