A 4-year study of the epidemiology of Vibrio cholerae in four rural areas of Bangladesh.

@article{Sack2003A4S,
  title={A 4-year study of the epidemiology of Vibrio cholerae in four rural areas of Bangladesh.},
  author={Richard Bradley Sack and Abul Kasem Siddique and Ira M. Longini and Azhar Nizam and Mohammad Yunus and M. Sirajul Islam and J. Glenn Morris and Afsar Ali and Anwar Huq and Gopinath Balakrish Nair and Firdausi Qadri and Shah M Faruque and David A. Sack and Rita R. Colwell},
  journal={The Journal of infectious diseases},
  year={2003},
  volume={187 1},
  pages={
          96-101
        }
}
How Vibrio cholerae spreads around the world and what determines its seasonal peaks in endemic areas are not known. These features of cholera have been hypothesized to be primarily the result of environmental factors associated with aquatic habitats that can now be identified. Since 1997, fortnightly surveillance in 4 widely separated geographic locations in Bangladesh has been performed to identify patients with cholera and to collect environmental data. A total of 5670 patients (53% <5 years… 

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References

SHOWING 1-10 OF 33 REFERENCES
Endemic cholera in rural Bangladesh, 1966-1980.
TLDR
While little progress has been made in understanding the mode of transmission of v. cholerae 01, and in identifying practices for prevention, fluid therapy in this area has decreased the case fatality rate significantly and provides guidance for similar programs elsewhere.
Large epidemic of cholera-like disease in Bangladesh caused by Vibrio cholerae 0139 synonym Bengal
  • Bangladesh Cholera Working Group International Centre for Diarrhoeal Diseases Resea, M. Albert, +10 authors K. Zaman
  • Medicine, Biology
    The Lancet
  • 1993
Ecology of Vibrio cholerae: role of aquatic fauna and flora
TLDR
In endemic areas of Bangladesh, cholera epidemics occur twice a year and have a regular seasonal pattern, but the reservoirs or sites of survival and multiplication of V. cholerae O1 between epidemics are not completely known.
Epidemic cholera in Guinea-Bissau: the challenge of preventing deaths in rural West Africa.
Cholera epidemics in Bangladesh: 1985-1991.
TLDR
It is shown that a high proportion (59%) of cholera patients during their illness in the rural areas were not visited by the government surveillance staff and that most were treated at home, and a higher case fatality ratio (14%) prior to intervention by qualified physicians during epidemics and an overallfatality ratio of 4%, despite the significant reduction by the intervention.
Epidemiology of endemic cholera.
TLDR
The theory is that the tanks of water are, in fact, the main means of spread of the infection; the seasonal fluctuations of the disease and possibly the limitations of the endemic area are the results of fluctuations in the pH of the tank water.
Epidemic and endemic cholera trends over a 33-year period in Bangladesh.
TLDR
Investigating cholera data collected over 33 years in Matlab, Bangladesh, revealed that both Inaba and Ogawa epidemics were followed 12 months later by epidemics of the same serotype, suggesting that the Inaba antigen should be maximized in cholERA vaccine designs.
Detection of Vibrio cholerae O1 in the aquatic environment by fluorescent-monoclonal antibody and culture methods
Vibrio cholerae O1 in plankton samples collected from ponds and rivers between February 1987 and January 1990 in Matlab, Bangladesh, was detected by the fluorescent-monoclonal antibody (FA)
Spread of Vibrio cholerae O139 Bengal in India.
TLDR
The extent of spread of V. cholerae O139 Bengal in India and its ability to swiftly disseminate leaves little doubt that this is the beginning of the eighth pandemic of cholera.
...
1
2
3
4
...