A 4-h hyperglycaemic excursion induces rapid and slow changes in major electrolytes in blood in healthy human subjects

@article{Caduff2011A4H,
  title={A 4-h hyperglycaemic excursion induces rapid and slow changes in major electrolytes in blood in healthy human subjects},
  author={Andreas Caduff and Lutz Heinemann and Mark S. Talary and Giacomo Di Benedetto and Hans U. Lutz and Sten S. Theander},
  journal={Acta Diabetologica},
  year={2011},
  volume={49},
  pages={333-339}
}
Hyperglycaemia is well known to cause reductions in plasma Na+ levels or even hyponatraemia due to an osmotically induced dilution of the interstitium and blood. It is, however, unclear whether this dilution is significantly counteracted by ion regulatory homeostatic mechanism(s) or not. Furthermore, the effects of moderate hyperglycaemia on other major ions are less well known. To further clarify these questions, we measured the changes in blood osmolarity and concentrations of Na+, K+, Cl… CONTINUE READING
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