A 4 and B 4 Are Potent Stimuli for H u m a n Monocyte Migration and Adhesion : Selective Inactivation

Abstract

Monocyte recruitment and adherence are important events in inflammatory and vascular diseases. Here, we evaluated the actions o f lipoxin A 4 (LXA4) and LXB4, a series o f lipoxygenase products from arachidonic acid generated by cell-cell interactions, on human monocytes. LXA 4 and LXB 4 (10 -7 M) each increased monocyte migration in chamber chemotaxis… (More)

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