A 3D microfluidic platform incorporating methacrylated gelatin hydrogels to study physiological cardiovascular cell-cell interactions.

@article{Chen2013A3M,
  title={A 3D microfluidic platform incorporating methacrylated gelatin hydrogels to study physiological cardiovascular cell-cell interactions.},
  author={M. B. Chen and Suthan Srigunapalan and Aaron R Wheeler and Craig A. Simmons},
  journal={Lab on a chip},
  year={2013},
  volume={13 13},
  pages={2591-8}
}
The cardiovascular system is particularly well-suited to modelling with microfluidic technologies, and much progress has been made to create microfluidic devices that mimic the microvasculature. In contrast, microfluidic platforms that model larger blood vessels and heart valves are lacking, despite the clear potential benefits of improved physiological relevance and enhanced throughput over traditional cell culture technologies. To address this need, we developed a bilayer membrane… CONTINUE READING