A 3D hybrid model for tissue growth: the interplay between cell population and mass transport dynamics.

@article{Cheng2009A3H,
  title={A 3D hybrid model for tissue growth: the interplay between cell population and mass transport dynamics.},
  author={Gang Cheng and Pauline Markenscoff and Kyriacos Zygourakis},
  journal={Biophysical journal},
  year={2009},
  volume={97 2},
  pages={401-14}
}
To provide theoretical guidance for the design and in vitro cultivation of bioartificial tissues, we have developed a multiscale computational model that can describe the complex interplay between cell population and mass transport dynamics that governs the growth of tissues in three-dimensional scaffolds. The model has three components: a transient partial differential equation for the simultaneous diffusion and consumption of a limiting nutrient; a cellular automaton describing cell migration… CONTINUE READING
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