A 2-step mechanism of arterial thrombus formation induced by human atherosclerotic plaques.

@article{Reininger2010A2M,
  title={A 2-step mechanism of arterial thrombus formation induced by human atherosclerotic plaques.},
  author={Armin J. Reininger and Isabell Bernlochner and Sandra M. Penz and Catherine Ravanat and Peter A. Smethurst and Richard W Farndale and Christian Gachet and Richard Brandl and Wolfgang Siess},
  journal={Journal of the American College of Cardiology},
  year={2010},
  volume={55 11},
  pages={
          1147-58
        }
}
OBJECTIVES The aim of this study was to understand the initial mechanism of arterial thrombus formation induced by vulnerable human atherosclerotic plaques to re-assess and improve current antithrombotic strategies. BACKGROUND Rupture of atherosclerotic plaques causes arterial thrombus formation that might lead to myocardial infarction and ischemic stroke. Atherothrombosis is considered as an inseparable tangle of platelet activation and coagulation processes, involving plaque components such… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 71 CITATIONS, ESTIMATED 52% COVERAGE

Platelets, Haemostasis and Inflammation

  • Cardiac and Vascular Biology
  • 2017
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2010
2019

CITATION STATISTICS

  • 2 Highly Influenced Citations

  • Averaged 5 Citations per year from 2017 through 2019

References

Publications referenced by this paper.
SHOWING 1-10 OF 40 REFERENCES

Dual role of collagen in factor XIIdependent thrombus formation

PE vanderMeijden, IC Munnix, JM Auger
  • Blood
  • 2009

Mechanisms of thrombus formation.

  • The New England journal of medicine
  • 2008