A 15-lncRNA signature predicts survival and functions as a ceRNA in patients with colorectal cancer

@article{Wang2018A1S,
  title={A 15-lncRNA signature predicts survival and functions as a ceRNA in patients with colorectal cancer},
  author={Xuning Wang and Jianguo Zhou and Maolin Xu and Yongfeng Yan and Liang Huang and Yanshen Kuang and Yuansheng Liu and Peng Li and Wei Zheng and Hongyi Liu and Baoqing Jia},
  journal={Cancer Management and Research},
  year={2018},
  volume={10},
  pages={5799 - 5806}
}
Purpose Colorectal cancer (CRC) is one of the most common malignant tumors worldwide. This study aimed to explore the prognostic value of lncRNAs in CRC. Material and methods We performed gene expression profiling to identify differentially expressed lncRNAs between 51 normal and 646 tumor tissues from The Cancer Genome Atlas database. Cox regression and robust likelihood-based survival models were used to find prognosis-related lncRNAs. A lncRNA signature was developed to predict the overall… 
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