A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. The MTA Cooperative Group. Multimodal Treatment Study of Children with ADHD.

@article{Jensen1999A1R,
  title={A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. The MTA Cooperative Group. Multimodal Treatment Study of Children with ADHD.},
  author={Pj Jensen and L. Eugene Arnold and John E. Richters and J B Severe and Donald R. Vereen and Benedetto Vitiello and Edler Schiller and Stephen P. Hinshaw and Gr Elliott and C. Keith Conners and K C Wells and John S. March and James M. Swanson and Timothy L. Wigal and Dennis P. Cantwell and H B Abikoff and J Hechtman and Ll Greeenhill and J H Newcorn and W. E. Pelham and Betsy Hoza and Hk Kraemer},
  journal={Archives of general psychiatry},
  year={1999},
  volume={56 12},
  pages={
          1073-86
        }
}
BACKGROUND Previous studies have demonstrated the short-term efficacy of pharmacotherapy and behavior therapy for attention-deficit/hyperactivity disorder (ADHD), but no longer-term (i.e., >4 months) investigations have compared these 2 treatments or their combination. METHODS A group of 579 children with ADHD Combined Type, aged 7 to 9.9 years, were assigned to 14 months of medication management (titration followed by monthly visits); intensive behavioral treatment (parent, school, and child… 

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References

SHOWING 1-10 OF 51 REFERENCES

National Institute of Mental Health Collaborative Multimodal Treatment Study of Children with ADHD (the MTA). Design challenges and choices.

The Collaborative Multimodal Treatment Study of Children with Attention Deficit Hyperactivity Disorder (ADHD), the MTA, is the first child multisite cooperative agreement treatment study of children conducted by the National Institute of Mental Health and compares state-of-the-art treatment with routine community care.

Long-term stimulant treatment of children with attention-deficit hyperactivity disorder symptoms. A randomized, double-blind, placebo-controlled trial.

The results of this long-term, placebo-controlled study of the central stimulant amphetamine in the treatment of ADHD indicate that there are remaining positive effects of the drug 15 months after starting treatment.

Comprehensive assessment of childhood Attention-Deficit Hyperactivity Disorder in the context of a multisite, multimodal clinical trial

As the largest randomized clinical trial conducted by the National Institute of Mental Health, the Multimodal Treatment Study of Children with ADHD (MTA) will yield data on a diverse sample of 576

The effects of a multimodal intervention with attention-deficit hyperactivity disorder children: a 9-month follow-up.

Nine months after the termination of the behavioral interventions and the withdrawal of the stimulant medication, limited support is found for the hypothesis that the combined conditions would produce greater maintenance of treatment gains than would medication alone.

NIMH collaborative multisite multimodal treatment study of children with ADHD: I. Background and rationale.

OBJECTIVE The National Institute of Mental Health's recently initiated 5-year, multisite, multimodal treatment study of children with attention-deficit hyperactivity disorder (MTA) is the first major

Behavioral, situational, and temporal effects of treatment of ADHD with methylphenidate.

Positive effects of MPH on behavior are evident in the classroom, but with MPH given twice daily, parents do not report that MPH improves behavior at home, and greater impact on home behavior may require three times daily MPH and combined treatments.

Medication treatment strategies in the MTA Study: relevance to clinicians and researchers.

Although the titration protocol is complex, the study's individual dosing approach and algorithms for openly managing ADHD children's medication over time will be of interest to clinicians in office practice.

Behavior therapy and methylphenidate in the treatment of children with ADHD

Behavior therapy delivered in school and home is not nearly as effective as methylphenidate for ADHD, but may be a useful adjunct to methylphenide, which was significantly superior to behavior therapy.

Pharmacotherapy of attention-deficit hyperactivity disorder across the life cycle.

The available literature indicates the important role of psychopharmacological agents in the reduction of the core symptoms of ADHD and associated impairments.

Bibliotherapy as an adjunct to stimulant medication in the treatment of attention-deficit hyperactivity disorder.

  • N. LongV. RickertE. Ashcraft
  • Psychology
    Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners
  • 1993
...