A 14,500 MW protein is coded by region E3 of group C human adenoviruses.

@article{Tollefson1990A1M,
  title={A 14,500 MW protein is coded by region E3 of group C human adenoviruses.},
  author={Ann E. Tollefson and P{\'e}ter Krajcsi and Mark Pursley and Linda R. Gooding and William S. M. Wold},
  journal={Virology},
  year={1990},
  volume={175 1},
  pages={19-29}
}
There is an ORF in the early region E3 transcription unit of human adenovirus 5 (Ad5) which could encode a protein of 14,500 MW (14.5K). This ORF is conserved in Ad5 and Ad2, both group C adenoviruses, and also in Ad3 and Ad7, both group B adenoviruses. To address whether the 14.5K protein is synthesized, we prepared antisera against synthetic peptides corresponding to residues 19-34 or 118-132 in the Ad5 version of 14.5K, and also against a TrpE-14.5K fusion protein expressed in Escherichia… CONTINUE READING

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