A 104-kDa diacylglycerol kinase containing ankyrin-like repeats localizes in the cell nucleus.

@article{Goto1996A1D,
  title={A 104-kDa diacylglycerol kinase containing ankyrin-like repeats localizes in the cell nucleus.},
  author={Kanako Goto and Hisatake Kondo},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1996},
  volume={93 20},
  pages={11196-201}
}
The cDNA corresponding to a fourth species of diacylglycerol (DG) kinase (EC 2.7.1.107) was isolated from cDNA libraries of rat retina and brain. This cDNA encoded a 929-aa, 104-kDa polypeptide termed DGK-IV. DGK-IV was different from previously identified mammalian DG kinase species, DGK-I, DGK-II, and DGK-III, in that it contained no EF-hand motifs but did contain four ankyrin-like repeats at the carboxyl terminus. These structural features of DGK-IV closely resemble the recently cloned, eye… CONTINUE READING
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