A 1024-channel CMOS microelectrode-array system with 26'400 electrodes for recording and stimulation of electro-active cells in-vitro

@article{Ballini2013A1C,
  title={A 1024-channel CMOS microelectrode-array system with 26'400 electrodes for recording and stimulation of electro-active cells in-vitro},
  author={Marco Ballini and Jonas Muller and Paolo Livi and Yihui Chen and Urs Frey and Amir Shadmani and I. L. Jones and Wei Gong and Michele Fiscella and Milos Radivojevic and Douglas J. Bakkum and Alexander Stettler and Flavio Heer and Andreas Hierlemann},
  journal={2013 Symposium on VLSI Circuits},
  year={2013},
  pages={C54-C55}
}
We report on a CMOS microelectrode array system chip for recording and stimulation of electrogenic cell cultures and tissues, featuring a sensing area of 8.09 mm2, composed of 26'400 electrodes at 17.5 μm pitch. A user-configurable selection of the electrodes can be routed to 32 stimulation units and to 1024 recording channels with 2.4 μVrms input-referred noise and 10-bit 20-kS/s A/D conversion. The system offers a versatile platform with excellent signal characteristics for a wide range of… CONTINUE READING
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