A 10-year retrospective study on benzocaine allergy in the United Kingdom.

  title={A 10-year retrospective study on benzocaine allergy in the United Kingdom.},
  author={Simmi Sidhu and Stephanie Shaw and John D. Wilkinson},
  journal={American journal of contact dermatitis : official journal of the American Contact Dermatitis Society},
  volume={10 2},
  • S. Sidhu, S. Shaw, J. Wilkinson
  • Published 1 June 1999
  • Medicine, Biology, Chemistry
  • American journal of contact dermatitis : official journal of the American Contact Dermatitis Society
Patch‐Test Reactions to Topical Anesthetics: Retrospective Analysis of Cross‐Sectional Data, 2001 to 2004
Over 50% of allergic reactions to topical anesthetics in this study would have been missed had benzocaine been used as a single screening agent, and cross‐reactivity patterns were not consistent with structural groups.
Lidocaine Contact Allergy Is Becoming More Prevalent
Investigating the epidemiology of topical anesthetic ACD in British Columbia, Canada and providing an approach for clinicians to deal with this problem found the proportion of ACD caused by lidocaine is higher than expected.
Hypersensitivity to local anaesthetics – update and proposal of evaluation algorithm
This review attempts to generate a comprehensive update on allergic reactions to LA and to present an algorithm that can be used for the evaluation of patients suspected with immediate‐ and delayed‐type immune reactions.
Cocaine Allergy in Drug-Dependent Patients and Allergic People.
Cross‐reactions among Parabens, para‐Phenylenediamine, and Benzocaine: A Retrospective Analysis of Patch Testing
The study demonstrated that the rate of cross‐reactions to parabens in PPD‐ and benzocaine‐positive patients combined is 2%, which is significant in the tested population but still falls within the previously reported rates of sensitivity to parbens in the general population.
Long-term trend in patch test reactions: a 32-year statistical overview (1970–2002), part II
A significant increase in positive reactions with carbamates, balsam of Peru, thimerosal, formaldehyde, imidazolidinyl urea, and methyldibromoglutaronitrile is observed and the rates of positive reactions to Dimethylol dimethyl (DMDM) hydantoin, diazolidinyl Urea,and methylchloroisothiazolone/methylisothiazoledone remained unchanged.
Contact Dermatitis to Medications and Skin Products
This review looks at various allergens in consumer products and reports current allergic contact dermatitis incidence and trends in North America, Europe, and Asia and examines the ingredients in the excipients of these products.
Allergens (Patch Test Studies) from the European Baseline Series
All areas of skin that are in contact with the allergen develop the rash, and the rash will disappear if you avoidcontact with the substance.
Allergic contact stomatitis.
Allergic contact stomatitis from the benzocainecontaining Orabase paste was considered the cause of the painful oral blisters because the condition resolved when use of the product was discontinued.
‘Deep impact’ contact allergy after subcutaneous injection of local anesthetics
A patient received injections of dexamethasone (LipotalonA) and lidocaine (LidojectA), and with 2 antirheumatic ointments containing phenylbutazone and dexamETHasone, respectively, 2 days after each set of injections, he developed itching, swelling, erythema and papules, lasting at least 4 days, at the injection sites.


Benzocaine—an unsatisfactory indicator of topical local anaesthetic sensitization for the U.K.
It is recommended that a non‐irritant ‘caine mix’containing benzocaine, cinchocaine and amethocaine should be included in the standard patch test series for the U.K.
In many cases of repeated rashes invariably following the ingestion of a drug, such as quinin or balsam of copaiba, the cause and effect are so obvious that further proof is seldom sought and generally is not necessary.
Preliminary patch testing with 25% and 15%‘caine’‐mixes
A 30-year old woman had a 6-month history of cheilitis accompanied by a burning feeling in the mouth, with the pulp of fruits usually eaten by the patient, and the kiwi fruit did not provoke any reaction on intact skin.
Proposal for a revised international standard series of patch tests
A “minimal” international standard series of 20 allergens is proposed, together with an “extended’ international standardseries of 14 allergens, for patch tests around the world.
Fisher's Contact Dermatitis
This edition is revised and updated with all the new allergens patients are likely to encounter and includes patient education instructions for dealing with common allergens.
Epidemiology of contact dermatitis.