A 10-year molecular survey of herpes simplex virus type 1 in Germany demonstrates a stable and high prevalence of genotypes A and B.

@article{SchmidtChanasit2009A1M,
  title={A 10-year molecular survey of herpes simplex virus type 1 in Germany demonstrates a stable and high prevalence of genotypes A and B.},
  author={Jonas Schmidt-Chanasit and Alexandra Bialonski and Patrick Heinemann and Rainer G Ulrich and Stephan G{\"u}nther and Holger F. Rabenau and Hans Wilhelm Doerr},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  year={2009},
  volume={44 3},
  pages={
          235-7
        }
}
BACKGROUND Recently three different herpes simplex virus type 1 (HSV-1) genotypes (A, B and C) were described on DNA sequence data of the glycoprotein E (gE), G (gG) and I (gI) genes. OBJECTIVE To type the circulating HSV-1 wild-type strains in Germany and to monitor potential changes in the molecular epidemiology over the past 10 years. STUDY DESIGN A total of 569 clinical HSV-1 isolates from a 10-year survey in Germany were genotyped by a PCR-based restriction fragment length polymorphism… CONTINUE READING

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